Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC443H746N112O121S4

DescriptionStandard

        MVKEKYKSNILLSATLLTTSLVALAFINAPFLAAQLGISTASAMAIINLIDGIRWVTVAMSIIAAASGVGAIGSALTAVVLQMIKKQGKAKAAAF
    

Molecular Weight9705.60 Da

Isoelectric Point (pI)10.22

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.27

Charge Density (pH 7.0) 0.0579

GRAVY Index1.01

Hydrophobic Moment 0.57

Boman Index0.38

Instability Index31.02

Aliphatic Index 132.74

Aromaticity 0.0526

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3686.35

LogP -31.17

H-bond Donors 129.0

H-bond Acceptors 131.0

Rotatable Bonds 327.0

Heavy Atoms 680.0

Ring Count 7.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051265 VERIFIED: NO

Provenance & Taxonomy

OrganismGracilibacillus halotolerans [Bacterium]

FamilyBacteriocin

Tax ID74386

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal