Peptide Database

Peptide NameCholecystokinin-58

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC286H456N86O85S3

DescriptionStandard

        RIDGTSDQKAVIGAMLAKYLQTRKAGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDF
    

Molecular Weight6555.40 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0491

GRAVY Index-0.59

Hydrophobic Moment 0.63

Boman Index-0.12

Instability Index38.31

Aliphatic Index 70.69

Aromaticity 0.0862

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2788.04

LogP -29.27

H-bond Donors 99.0

H-bond Acceptors 92.0

Rotatable Bonds 215.0

Heavy Atoms 460.0

Ring Count 10.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013271 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeiana [Animal]

FamilyGastrin/cholecystokinin

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsTyr52 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0128796 VERIFIED: YES

Provenance & Taxonomy

OrganismAquarana catesbeiana [Animal]

FamilyCholecystokinin

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods52:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min