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MYP_092288
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Basic Information
Casein alpha-s2 [182-184]
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C18H27N3O6
Standard
Sequence
TVY
Physicochemical Analysis
381.42 Da
5.18
-0.60
-0.79
-0.2009
0.73
0.36
0.43
-18.47
96.67
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
161.98
-0.65
6.0
6.0
9.0
27.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024815 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
15 μM
IC50
RECORD: Rec_0027116 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0154811 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
15.0
IC50
PaperTauzin J., Miclo L., Gaillard J.-L.. Angiotensin-I-converting enzyme inhibitory peptides from tryptic hydrolysate of bovine alphaS2-casein. FEBS Lett., 531, 369-374.
RECORD: Rec_0211563 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
20000 μM
IC50
PaperStructural requirements of Angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides. PMID16448176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16448176/
RECORD: Rec_0232309 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
15 μM
IC50
PaperAngiotensin-I-converting enzyme inhibitory peptides from tryptic hydrolysate of bovine ?S2-casein
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