Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length438 amino acids

Chemical FormulaC2219H3472N582O613S9

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAVLEKELAQLKLPDISGDFPIRRVGKVHYEISRLELRSFHLPYSRISLVPKVGLQVSISNAFAEVDGNWRVKIHFIRDHGSFDLKVENIYIKINLKLGSDASGKPTIDTSDCSTRISKVRVHFSGKFGWLYNLFHSVIEARFRKALESKVCENVVSSVHGELQPYIQTLPVTARIDAIAGIDYSLVAPPTATAQSLDVDLKGKFFSLTHPSTIPFPPLALAFPPDHNRMVYFGASSYFFNTAGFVYHAAGALVFEITDSMIPKGVDFHLNTSTFSAFVPQLEKMYPDMLMKLRLSAPSAPFLNIGPEGLSLKPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVIDVKSSHVVGNLKVGSSFPPPSLRSQVRTLQSIMNIFASSILLPRFNARLEQGFPLPLPDRIQLSNMLVQFHQ
    

Molecular Weight48399.42 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)7.63

Net Charge (pH 7.4) 6.61

Charge Density (pH 7.0) 0.0174

GRAVY Index0.13

Hydrophobic Moment 0.74

Boman Index0.14

Instability Index36.59

Aliphatic Index 101.92

Aromaticity 0.0982

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072060 VERIFIED: NO

Provenance & Taxonomy

OrganismGrus americana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria