Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC440H693N121O135S14

DescriptionStandard

        MKAFSIAVAVTLVLAFVCIVQSSAVPFTGVGELEEAGGNDTPVEAHQEVSMESWMQPCPLSNTQMEKERQSHLSLCRYCCNCCKNKGCGFCCRF
    

Molecular Weight10286.85 Da

Isoelectric Point (pI)5.57

Net Charge (pH 7.0)-2.41

Net Charge (pH 7.4) -2.89

Charge Density (pH 7.0) -0.0256

GRAVY Index0.11

Hydrophobic Moment 0.57

Boman Index0.09

Instability Index34.36

Aliphatic Index 68.40

Aromaticity 0.0745

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4083.89

LogP -45.17

H-bond Donors 148.0

H-bond Acceptors 149.0

Rotatable Bonds 337.0

Heavy Atoms 710.0

Ring Count 14.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283653 VERIFIED: NO

Provenance & Taxonomy

OrganismPoecilia mexicana [Bacterium]

FamilyHepcidin

Tax ID48701

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal