Peptide Database

Peptide NameHNHc domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1519 amino acids

Chemical FormulaC7104H10992N2006O2336S25

DescriptionStandard

        MPAAEDDNNLACYPVYWPVNGGDPQLDWFNKYRVIAVSTADPAGRNLTVENAYTYEGPAWHYNDDPFTKEKERTWSSWRGYQKVTAHTGAVGNTRSKTVSLYLQGMHGDRLLAKDANGNPLTRSVTVAGIDIDNETGTTGDELTVGDVTDSEHYAGRLRQKITYDGATAVSNQINDFWYKQTASQQKSYAHVTAGYTRTARTYTNTYLTAAQKWRTTAVSHAFDGYGMVVRTDNHGDWTAAGDETCTRTWYARNDAKGLTSLASRSRTVGQACSVTDDQLKMPTSITHKYTSAEAPDQRGDVLSDTAVAYDDTAATGWTADQTPTLGLPTWTGRTKGYPGAVAGSTADRHPTGWQTVTKVTYDGATAKLGRPLTVTDAAGKVTTTAYVPAAAGPLTAMIVTKPTLVNGQAHKIYTYYDPARGSVTQTLDANLKRTEHTYDALGRLAATWAPNRSKSGGDTATATFVYGINQTDNPSWTSVSTLKADGQTYTTSYSLVDSLLRPLQTQSPAPNGGRILTDTRYNDRGLAYETYADIFDSTTAPSSTWTRAEYGGAPQQTQVEFDGLGRQVKSTLLVKGVPKFAPVATTYTGDSVATTAQQGGTATRTITDALGRTTETRTYAGSQPDDTAYGATLGTSYTSLKYGYFRDGKQKQITRPDNAKWSYTYDLYGRQDAATDPDKGTSFTSFTDLDQIQTTKDAANRVLVYGYDEIGRKTGLWQNSASDANRLAEWTYDSLLKGLPDASIRYTGGKAQAGSKAYTKKVTAYDSMSRPITTTLTLPADDPLVASGAVTATSTAKVDYRLDGMVGSTTEPAAGGLAGEIVSTSYNSFGLPIGLSGTSGYLLGASYTDLGQVQQLTLGTSTATGTKKVFLTNFYEEGTGRLTDADVDDQTRGAVRDTAYTYDPAGNVTSIFDHANTGNGADFQCFTHDGQRRLTEAWTPKTADCATSGRTVANLGGAAPYWTSYTYNAAGQRATEKQNTATPVTRTYCYDTTRTHALKATTTDGNCSDETARYTYDASGNTTTRVETAGSTTSQSLTWSAEGKLTKLTEGTATTDYLYDADGELLIRRASGTSGETVLYLGATEVHVKGTKKWANRYYTAAGSTIALRTNETGTEKLHFLAADHHNTGNLSLTADATQALTKRYTTPFGAARGTTSGTWPDDKTFLGKPTDAGTGLTHIGAREYDPTIGQFISVDPALVLDQHQSLNGYAYANNTPVTSSDSTGLWLDDGTGHNEPGGGPGGGQSSTPGVPEGGTGPGGCYYQCDSGTDSNGTVETSSGNPGSTNCIPVYTCQGLPKYKMNVGSEYGVDGPEMTQEETAAANTACSMVPVVGIPCDMREIATSTENGDAGGVVLAALGVVPFLDWVKVPKAIDGAVTAQKLRNMPGAVTGGSRLKDVSGKWLLGTHGNVGKIPGQVARGLQGRQFNSFDKFREAFWLEVAKHPKLVNQFIPGNRALIKQGKAPRTVPRQAIGKNNYYSLHHVNPIHNGGGVYDLDNIIVVTPRYHREVLDPVFHEER
    

Molecular Weight162676.94 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-13.08

Net Charge (pH 7.4) -15.28

Charge Density (pH 7.0) -0.0086

GRAVY Index-0.55

Hydrophobic Moment 0.70

Boman Index-0.02

Instability Index22.68

Aliphatic Index 61.99

Aromaticity 0.0889

Extinction Coeff. Reduced 267700.00

Extinction Coeff. Oxidized 268450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252431 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. QHH-9511 [Bacterium]

FamilyPyocin/Colicin

Tax ID2684468

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Hydrolase Non-hemolytic Non-ribosomal