Peptide Database

Peptide NameHill-Def 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC183H291N53O58S6

DescriptionStandard

        QLPCDYLSGLGFGEDACNTDCIAKGHKSGFCTGLVCRCRTL
    

Molecular Weight4353.98 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.56

Charge Density (pH 7.0) -0.0051

GRAVY Index0.05

Hydrophobic Moment 0.48

Boman Index0.06

Instability Index38.40

Aliphatic Index 69.02

Aromaticity 0.0732

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1779.81

LogP -21.62

H-bond Donors 68.0

H-bond Acceptors 65.0

Rotatable Bonds 142.0

Heavy Atoms 300.0

Ring Count 5.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282381 VERIFIED: YES

Provenance & Taxonomy

OrganismHermetia illucens [Animal]

FamilyDefensin

Tax ID343691

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa ATCC 9027

Activity32 μM

MethodIC50

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