Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length106 amino acids

Chemical FormulaC531H844N150O150S3

DescriptionStandard

        PRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELG
    

Molecular Weight11825.49 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)1.23

Net Charge (pH 7.4) 0.99

Charge Density (pH 7.0) 0.0116

GRAVY Index-0.23

Hydrophobic Moment 0.45

Boman Index0.02

Instability Index50.14

Aliphatic Index 91.98

Aromaticity 0.0660

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4750.12

LogP -45.18

H-bond Donors 161.0

H-bond Acceptors 157.0

Rotatable Bonds 375.0

Heavy Atoms 834.0

Ring Count 23.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211955 VERIFIED: NO

Provenance & Taxonomy

OrganismPtilorrhoa leucosticta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria