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MYP_092047
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Basic Information
PR-bombesin
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Standard
16 amino acids
C89H134N26O19S
Standard
Sequence
QKKPPRPPQWAVGHFM
Physicochemical Analysis
1904.24 Da
11.17
2.85
2.59
0.1778
-1.22
0.50
-0.15
26.92
24.38
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
709.25
-4.26
22.0
24.0
55.0
135.0
8.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016524 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
PR
161274
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Smooth muscle contraction
PaperR. Lai et al. / Peptides 23 (2002) 437-442. A novel proline rich bombesin-related peptide (PR-bombesin) from toad Bombina maxima
RECORD: Rec_0038107 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
161274
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
The N-terminus is a pyroglutamate. Discovery: Such peptides are amphibian homologs of the mammalian gastrin-releasing peptide. It also plays a role in defense and has neuro-endocrological functions (Life Sci. 2006; 78: 1953-56)
Bio-Activity Profile
Antimicrobial Antifungal
B.pyocyaneus CMCCB10104
150 μg/mL
MIC
PaperA novel proline rich bombesin-related peptide (PR-bombesin) from toad Bombina maxima.
RECORD: Rec_0062293 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
161274
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
The N-terminus is a pyroglutamate. Discovery: Such peptides are amphibian homologs of the mammalian gastrin-releasing peptide. It also plays a role in defense and has neuro-endocrological functions (Life Sci. 2006; 78: 1953-56)
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922
50 μg/mL
MIC
PaperA novel proline rich bombesin-related peptide (PR-bombesin) from toad Bombina maxima.
RECORD: Rec_0111585 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
161274
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
The N-terminus is a pyroglutamate. Discovery: Such peptides are amphibian homologs of the mammalian gastrin-releasing peptide. It also plays a role in defense and has neuro-endocrological functions (Life Sci. 2006; 78: 1953-56)
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 2592
25 μg/mL
MIC
PaperA novel proline rich bombesin-related peptide (PR-bombesin) from toad Bombina maxima.
RECORD: Rec_0132570 VERIFIED: NO
Provenance & Taxonomy
Yunnan firebelly [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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