Peptide Database

Peptide Name[D-Ala2,Ala15]Cyclo(Lys21-Asp25)GRF(1-29)-NH2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC150H240N40O41S3

DescriptionStandard

        YADAIFTNSYRKVLAQLSARCYCLKLLQC
    

Molecular Weight3355.95 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)2.73

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0940

GRAVY Index0.28

Hydrophobic Moment 0.49

Boman Index0.04

Instability Index10.38

Aliphatic Index 104.48

Aromaticity 0.1379

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1341.91

LogP -11.11

H-bond Donors 51.0

H-bond Acceptors 47.0

Rotatable Bonds 110.0

Heavy Atoms 234.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296969 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGHRH/CRF

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other ModsComposite modified token cyclo; Mixed L/D stereochemistry with D-annotated positions 2

Bio-Activity Profile

Function

Endocrine

MethodHPLC

Half-LifePorcine plasma, in vitro; >14400 s