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MYP_092032
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Basic Information
Bacteriocin lacticin 3147 A2 (LtnA2; Bacteriocin; Preclinical)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
29 amino acids
C126H212N34O43S3
Standard
Sequence
TTPATPAISILSAYISTNTCPTTKCTRAC
Physicochemical Analysis
2987.43 Da
8.65
1.37
1.13
0.0471
0.21
0.34
0.12
54.50
67.59
0.0345
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1225.52
-18.22
47.0
48.0
88.0
206.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0023467 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Amidation
None
There are one 2-oxobutanoic acid (T1), two 2,3-dehydrobutyrines (T2; T5), two 2,3-dehydroalanines (S9; S12), one Lanthionine (S16-C20) and two Beta-methyllanthionines (T22-C24; T26-C29)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactobacillus
PaperPubMed PMID: 10971756 | PubMed PMID: 15023056 | PubMed PMID: 10608807 PMID10971756;15023056;10608807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10971756/
RECORD: Rec_0104255 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactococcus lactis strain AM2
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ3888
RECORD: Rec_0125184 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Amidation
None
There are one 2-oxobutanoic acid (T1), two 2,3-dehydrobutyrines (T2; T5), two 2,3-dehydroalanines (S9; S12), one Lanthionine (S16-C20) and two Beta-methyllanthionines (T22-C24; T26-C29)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Leuconostoc
PaperPubMed PMID: 10971756 | PubMed PMID: 15023056 | PubMed PMID: 10608807 PMID10971756;15023056;10608807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10971756/
RECORD: Rec_0134319 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0182403 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Amidation
None
There are one 2-oxobutanoic acid (T1), two 2,3-dehydrobutyrines (T2; T5), two 2,3-dehydroalanines (S9; S12), one Lanthionine (S16-C20) and two Beta-methyllanthionines (T22-C24; T26-C29)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactococcus
PaperPubMed PMID: 10971756 | PubMed PMID: 15023056 | PubMed PMID: 10608807 PMID10971756;15023056;10608807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10971756/
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