Peptide Database

Peptide Namehuman Histatin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC175H258N68O52

DescriptionStandard

        DSHDKRHHEHRRKFHEKHHSHRGYRSNYLDEN
    

Molecular Weight4146.35 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)2.46

Net Charge (pH 7.4) 1.84

Charge Density (pH 7.0) 0.0770

GRAVY Index-2.71

Hydrophobic Moment 0.41

Boman Index-0.75

Instability Index47.94

Aliphatic Index 12.19

Aromaticity 0.0938

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1993.55

LogP -23.58

H-bond Donors 72.0

H-bond Acceptors 62.0

Rotatable Bonds 141.0

Heavy Atoms 295.0

Ring Count 11.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363901 VERIFIED: YES

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyHistatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)