Peptide Database

Peptide NameVarv A

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC116H185N35O40S6

DescriptionStandard

        GLPCVGETCVGGTCNTPGCSCSWPVCTRN
    

Molecular Weight2902.31 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0102

GRAVY Index0.15

Hydrophobic Moment 0.26

Boman Index0.15

Instability Index31.82

Aliphatic Index 43.45

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1174.30

LogP -18.65

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 84.0

Heavy Atoms 197.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053673 VERIFIED: YES

Provenance & Taxonomy

OrganismViola arvensis [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Anticancer Cytotoxic

Target10 cancer cell lines

RECORD: Rec_0260917 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer