Peptide Database

Peptide Nameaurein 3.1

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC83H138N22O22

DescriptionStandard

        GLFDIVKKIAGHIAGSIG
    

Molecular Weight1796.12 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0470

GRAVY Index0.86

Hydrophobic Moment 0.60

Boman Index0.42

Instability Index29.68

Aliphatic Index 135.56

Aromaticity 0.0556

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 696.27

LogP -4.97

H-bond Donors 24.0

H-bond Acceptors 24.0

Rotatable Bonds 61.0

Heavy Atoms 127.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0261242 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria aurea; Litoria raniformis [Animal]

FamilyAurein

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer

PaperRozek T., Wegener K.L., Bowie J.H., Olver I.N., Carver J.A., Wallace J.C., Tyler M.J.;. "The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2."; Eur. J. Biochem. 267:5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/