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MYP_091921
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Basic Information
Lantibiotic ancovenin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibiotic activity
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
19 amino acids
C85H129N23O29S3
Standard
Sequence
CVQSCSFGPLTWSCDGNTK
Physicochemical Analysis
2033.27 Da
5.82
-0.27
-0.52
-0.0142
-0.17
0.17
0.07
56.24
35.79
0.1053
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
844.77
-12.16
32.0
32.0
62.0
140.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0201388 VERIFIED: NO
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/P38655/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0224587 VERIFIED: YES
Provenance & Taxonomy
Streptomyces sp. A647P-2 [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP00056
RECORD: Rec_0326964 VERIFIED: NO
Provenance & Taxonomy
Streptomyces sp. [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ6399
RECORD: Rec_0328062 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperThe structure of ancovenin, a new peptide inhibitor of angiotensin I converting enzyme
RECORD: Rec_0370534 VERIFIED: NO
Provenance & Taxonomy
Streptomyces albogriseolu [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
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