Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC549H869N145O169S5

DescriptionStandard

        PDLSGYEKYGLGNVKYTISRIHVTAVDFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTMYISKVFVTAIFSTPLDHMGRTSIALTSCSTTSGDTDIKPNGQN
    

Molecular Weight12364.97 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)2.12

Net Charge (pH 7.4) 1.93

Charge Density (pH 7.0) 0.0186

GRAVY Index-0.03

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index12.48

Aliphatic Index 84.65

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5022.29

LogP -56.68

H-bond Donors 180.0

H-bond Acceptors 178.0

Rotatable Bonds 403.0

Heavy Atoms 868.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076250 VERIFIED: NO

Provenance & Taxonomy

OrganismHemiprocne comata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria