Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC356H573N109O99S8

DescriptionStandard

        MRTSVLLFALLFFMSQVLPVRGRFKEICERPNGSCRHNCISTEVYAGRCLDGNPCCLPLGNQPRIRGTVPQDH
    

Molecular Weight8220.55 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0496

GRAVY Index-0.12

Hydrophobic Moment 0.46

Boman Index-0.03

Instability Index46.85

Aliphatic Index 81.37

Aromaticity 0.0685

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3334.33

LogP -34.92

H-bond Donors 121.0

H-bond Acceptors 113.0

Rotatable Bonds 265.0

Heavy Atoms 572.0

Ring Count 13.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370180 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence