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MYP_091829
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Basic Information
Phylloseptin-S4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C94H154N24O22S
Standard
Sequence
FLSMIPHIVSGVAALAKHL
Physicochemical Analysis
2004.44 Da
8.76
0.93
0.63
0.0491
1.32
0.44
0.51
26.62
148.95
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
702.17
-3.09
24.0
26.0
63.0
141.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0278151 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Escherichia coli ATCC 25922
25 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0285504 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
S. pyogenes ATCC 19615
3.1 μM
MIC
PaperStructure, antimicrobial activities and mode of interaction with membranes of novel [corrected] phylloseptins from the painted-belly leaf frog, Phyllomedusa sauvagii
RECORD: Rec_0313184 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania braziliensis MHOM/BR/75/M2904
17.2 μM
IC50
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0336784 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Staphylococcus aureus ATCC 43300
6.25 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0343853 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Escherichia coli ML-35p
25 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
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