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MYP_091829
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Basic Information
Phylloseptin-S4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C94H154N24O22S
Standard
Sequence
FLSMIPHIVSGVAALAKHL
Physicochemical Analysis
2004.44 Da
8.76
0.93
0.63
0.0491
1.32
0.44
0.51
26.62
148.95
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
702.17
-3.09
24.0
26.0
63.0
141.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0180385 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
C. parapsilosis ATCC 22019
50 μM
MIC
PaperStructure, antimicrobial activities and mode of interaction with membranes of novel [corrected] phylloseptins from the painted-belly leaf frog, Phyllomedusa sauvagii
RECORD: Rec_0183277 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: THP-1
23 μM
IC50
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0183560 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Enterococcus faecalis ATCC 29212
50 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
RECORD: Rec_0205064 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Staphylococcus aureus
6.25 μM
MIC
PaperStructure, antimicrobial activities and mode of interaction with membranes of novel [corrected] phylloseptins from the painted-belly leaf frog, Phyllomedusa sauvagii
RECORD: Rec_0205158 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Staphylococcus aureus ATCC BAA-44
6.25 μM
MIC
PMID23967105 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23967105/
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