Peptide Database

Peptide NameIZN36

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC323H555N91O92

DescriptionStandard

        IKKEIEAIKKEQEAIKKKIEAIEKEISGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARIL
    

Molecular Weight7185.42 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)2.86

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0461

GRAVY Index-0.35

Hydrophobic Moment 0.60

Boman Index-0.07

Instability Index67.85

Aliphatic Index 132.26

Aromaticity 0.0161

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3053.72

LogP -22.70

H-bond Donors 101.0

H-bond Acceptors 96.0

Rotatable Bonds 266.0

Heavy Atoms 506.0

Ring Count 3.0

Amide Bonds 72.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0416372 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

Target293T

Activity0.035 μM

MethodIC50

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2