Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC350H549N103O106S4

DescriptionStandard

        QHWSYGWLPGGKRSVGEVEATFRMMDSGDAVLSIPMDSPMERLSPIHIVSEVDAEGLPLKEQRFPNRRGRD
    

Molecular Weight8023.99 Da

Isoelectric Point (pI)5.61

Net Charge (pH 7.0)-2.04

Net Charge (pH 7.4) -2.37

Charge Density (pH 7.0) -0.0288

GRAVY Index-0.63

Hydrophobic Moment 0.55

Boman Index-0.09

Instability Index61.26

Aliphatic Index 68.59

Aromaticity 0.0704

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3343.50

LogP -33.28

H-bond Donors 116.0

H-bond Acceptors 110.0

Rotatable Bonds 262.0

Heavy Atoms 563.0

Ring Count 15.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111427 VERIFIED: YES

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyProgonadoliberin

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour