Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 27.3

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC231H372N74O66S8

DescriptionStandard

        QIYISDPCAGGVHRCYEPCEKKKCRLPHKCINGRCTCYVGRNVCAISSH
    

Molecular Weight5498.40 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.94

Net Charge (pH 7.4) 4.46

Charge Density (pH 7.0) 0.1009

GRAVY Index-0.40

Hydrophobic Moment 0.63

Boman Index-0.13

Instability Index28.69

Aliphatic Index 61.63

Aromaticity 0.0612

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2254.25

LogP -25.72

H-bond Donors 87.0

H-bond Acceptors 82.0

Rotatable Bonds 178.0

Heavy Atoms 379.0

Ring Count 9.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038894 VERIFIED: NO

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Channel blocker