Peptide Database

Peptide NamePotassium channel toxin alpha-KTx Ctri9577

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC181H300N62O55S7

DescriptionStandard

        QIHTNQPCTSNNTRCRTYCIKVHKINSGKCMNSKCVCHP
    

Molecular Weight4449.16 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.96

Net Charge (pH 7.4) 5.51

Charge Density (pH 7.0) 0.1527

GRAVY Index-0.77

Hydrophobic Moment 0.39

Boman Index-0.23

Instability Index25.78

Aliphatic Index 44.87

Aromaticity 0.0256

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1928.93

LogP -27.46

H-bond Donors 72.0

H-bond Acceptors 71.0

Rotatable Bonds 147.0

Heavy Atoms 305.0

Ring Count 6.0

Amide Bonds 45.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0391530 VERIFIED: YES

Provenance & Taxonomy

OrganismChaerilus tricostatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

TargetMKv1, KCNA3

Activity0.00049 μM

MethodIC50