Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC463H748N128O135S8

DescriptionStandard

        MRTLGLLTALLLMALQAQAGPLQKRPEEAPVQEQPELKEDDVTISIIWDKNAFLEAPVLGRLVTCSCRRAFCDLGERHIGTCFLRDNLYAFCCS
    

Molecular Weight10524.19 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-2.45

Net Charge (pH 7.4) -2.83

Charge Density (pH 7.0) -0.0261

GRAVY Index0.07

Hydrophobic Moment 0.68

Boman Index0.05

Instability Index64.00

Aliphatic Index 100.74

Aromaticity 0.0638

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4212.80

LogP -36.84

H-bond Donors 150.0

H-bond Acceptors 142.0

Rotatable Bonds 348.0

Heavy Atoms 734.0

Ring Count 13.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379883 VERIFIED: NO

Provenance & Taxonomy

OrganismOtolemur garnettii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence