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MYP_091744
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Basic Information
Unnamed
Antimicrobial
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C93H142N30O19S4
Standard
Sequence
KWCFRVCYRGICYRRC
Physicochemical Analysis
2112.57 Da
9.58
4.72
4.45
0.2948
-0.27
0.65
-0.31
13.43
42.50
0.2500
8480.00
8730.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
829.69
-5.23
37.0
28.0
66.0
146.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081017 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 12.5%, T 37.5%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiparasitic Toxic Antimicrobial Hemolytic Antitrypanosomal Antileishmanial
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0171656 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachyplesin
6853
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal Anti-Trypanosoma cruzi
Trypanosoma cruzi Y (bloodstream trypomastigote form)
9.3 μM
LD50; MTT assay
PMID17888907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17888907/
RECORD: Rec_0376905 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachyplesin
6853
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antileishmanial
Leishmania braziliensis 2904 (promastigote)
>12.5 μM
LD50; MTT assay
PMID17888907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17888907/
RECORD: Rec_0411683 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Tachyplesin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17888907/ PMID17888907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17888907/