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MYP_091689
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Basic Information
myticin B from Mytilum edulis
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C193H295N63O51S8
Standard
Sequence
HPHVCTSYYCSKFCGTAGCTRYGCRNLHRGKLCFCLHCSR
Physicochemical Analysis
4570.32 Da
9.10
6.02
5.50
0.1506
-0.27
0.74
-0.09
28.63
39.00
0.1250
4470.00
4970.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1828.95
-21.91
76.0
69.0
143.0
315.0
10.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0223349 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli D31
20-10 μM
MBC
PMID10491159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10491159/
RECORD: Rec_0229957 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Protozoan P-marinus
>20 μM
MIC
PaperMyticin, a novel cysteine-rich antimicrobial peptide isolated from haemocytes and plasma of the mussel Mytilus galloprovincialis
RECORD: Rec_0233337 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Myticin
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
1-2 μM
MIC
PMID10491159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10491159/
RECORD: Rec_0235115 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0245981 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
29158
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Micrococcus luteus
1-2 μM
MIC
PaperMyticin, a novel cysteine-rich antimicrobial peptide isolated from haemocytes and plasma of the mussel Mytilus galloprovincialis
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