Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC363H573N115O94S13

DescriptionStandard

        MNKTRFGFFFILLILLASQMMVQTEGRHCESKSHRFKGMCMSDHNCASVCHVEGFPGGNCRGFRRRCFCKKRC
    

Molecular Weight8468.99 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)8.77

Net Charge (pH 7.4) 8.23

Charge Density (pH 7.0) 0.1202

GRAVY Index-0.24

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index64.89

Aliphatic Index 46.71

Aromaticity 0.1096

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3396.01

LogP -35.78

H-bond Donors 130.0

H-bond Acceptors 120.0

Rotatable Bonds 288.0

Heavy Atoms 585.0

Ring Count 13.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178343 VERIFIED: NO

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

Tax ID3880

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence