Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC306H493N81O75S5

DescriptionStandard

        VRIHYLLFALLFLFLVPVPCHGGIINTLQKYYCRVRGGQCAVLSCLPKEEQIGKCSTKK
    

Molecular Weight6667.01 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)5.86

Net Charge (pH 7.4) 5.46

Charge Density (pH 7.0) 0.0993

GRAVY Index0.40

Hydrophobic Moment 0.63

Boman Index0.15

Instability Index57.26

Aliphatic Index 113.90

Aromaticity 0.1017

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2486.48

LogP -16.15

H-bond Donors 91.0

H-bond Acceptors 88.0

Rotatable Bonds 219.0

Heavy Atoms 467.0

Ring Count 11.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262574 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal