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MYP_091520
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Basic Information
IsCT1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Short antimicrobial peptide (group 4) family
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C74H118N16O17
Standard
Sequence
ILGKIWEGIKSLF
Physicochemical Analysis
1503.83 Da
8.59
0.76
0.55
0.0585
0.78
0.59
0.41
-2.08
150.00
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
537.88
-0.21
19.0
18.0
51.0
107.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0377412 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. aerogenes
100 μg/mL
MIC
PMID28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28657596/
RECORD: Rec_0377700 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
1 μM
MIC
PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
RECORD: Rec_0392021 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Opisthacanthus madagascariensi [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P. aeroginosa ATCC 27853
100 μM
MIC
PaperIsCT, a novel cytotoxic linear peptide from scorpion Opisthacanthus madagascariensis.
RECORD: Rec_0392886 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Opisthacanthus madagascariensi [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli CCT 1371, Escherichia coli ATCC 25922
5-10 μM
MIC
PaperIsCT, a novel cytotoxic linear peptide from scorpion Opisthacanthus madagascariensis.
RECORD: Rec_0396644 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
2 μM
MIC
PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
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