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MYP_091520
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Basic Information
IsCT1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Short antimicrobial peptide (group 4) family
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C74H118N16O17
Standard
Sequence
ILGKIWEGIKSLF
Physicochemical Analysis
1503.83 Da
8.59
0.76
0.55
0.0585
0.78
0.59
0.41
-2.08
150.00
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
537.88
-0.21
19.0
18.0
51.0
107.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0116925 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 69.2%, E 0.0%, T 0.0%, C 30.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0138300 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. typhimurium
1 μM
MIC
PMID15369808 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15369808/
RECORD: Rec_0179617 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Serratia marcescens ATCC 4112
0.36
MIC
PMID31642159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31642159/
RECORD: Rec_0183920 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
0.78
MIC
PMID31642159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31642159/
RECORD: Rec_0184247 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/14637016/ PMID14637016 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14637016/
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