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MYP_091476
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
22 amino acids
C101H158N28O32S3
Standard
Sequence
KRGSGWIATITDDCPNSVFVCC
Physicochemical Analysis
2372.70 Da
5.94
-0.27
-0.52
-0.0122
0.20
0.41
0.11
34.87
66.36
0.0909
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
967.95
-11.51
37.0
35.0
73.0
164.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006619 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 18.2%, E 9.1%, T 45.5%, C 27.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0182901 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0204255 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
adsorption to hydrophobic resin XAD-2 followed by methan-ol elution. Chemical modification: one lanthionine and two beta-methyllanthionine residues
Bio-Activity Profile
Antimicrobial
most Streptococcus pyogenes strains
PaperIsolation and characterization of the lantibiotic salivaricin A and its structural gene salA from Streptococcus salivarius 20P3
RECORD: Rec_0220895 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 8357242 PMID8357242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8357242/
RECORD: Rec_0377958 VERIFIED: NO
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]; Bacteria [Bacterium]
2; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial