Peptide Database

Peptide NameNisin A

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC146H240N42O45S7

DescriptionStandard

        VTSVFMCTPGCVTGALMGCNLQTATCNCHVHISK
    

Molecular Weight3528.18 Da

Isoelectric Point (pI)7.83

Net Charge (pH 7.0)0.86

Net Charge (pH 7.4) 0.47

Charge Density (pH 7.0) 0.0252

GRAVY Index0.67

Hydrophobic Moment 0.23

Boman Index0.27

Instability Index38.34

Aliphatic Index 74.41

Aromaticity 0.0294

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1369.09

LogP -18.04

H-bond Donors 52.0

H-bond Acceptors 55.0

Rotatable Bonds 111.0

Heavy Atoms 240.0

Ring Count 4.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0303432 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus intermedius [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)