Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC927H1401N207O280S9

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTCSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTAEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20213.84 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.25

Net Charge (pH 7.4) -14.54

Charge Density (pH 7.0) -0.0778

GRAVY Index0.33

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index46.97

Aliphatic Index 94.43

Aromaticity 0.1366

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7680.84

LogP -79.37

H-bond Donors 261.0

H-bond Acceptors 275.0

Rotatable Bonds 639.0

Heavy Atoms 1423.0

Ring Count 37.0

Amide Bonds 196.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0340472 VERIFIED: NO

Provenance & Taxonomy

OrganismFregetta grallaria (White-bellied storm-petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria