Peptide Database

Peptide NameAntitumor antibiotic C-1027 apoprotein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC450H694N122O160S4

DescriptionStandard

        APAFSVSPASGLSDGQSVSVSVSGAAAGETYYIAQCAPVGGQDACNPATATSFTTDASGAASFSFVVRKSYTGSTPEGTPVGSVDCATAACNLGAGNSGLDLGHVALTFG
    

Molecular Weight10501.31 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-5.15

Net Charge (pH 7.4) -5.46

Charge Density (pH 7.0) -0.0468

GRAVY Index0.25

Hydrophobic Moment 0.40

Boman Index0.24

Instability Index34.89

Aliphatic Index 64.91

Aromaticity 0.0727

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4405.39

LogP -68.69

H-bond Donors 156.0

H-bond Acceptors 160.0

Rotatable Bonds 322.0

Heavy Atoms 736.0

Ring Count 15.0

Amide Bonds 115.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276764 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces globisporus [Bacterium]

Familyneocarzinostatin family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide36-45; 86-91

Bio-Activity Profile

Function

Antimicrobial neocarzinostatin family Antibacterial Host defense