Peptide Database

Peptide NameSLAY-screened peptide P89

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC51H68N14O13

DescriptionStandard

        TQLYHTWH
    

Molecular Weight1085.17 Da

Isoelectric Point (pI)6.61

Net Charge (pH 7.0)-0.43

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0536

GRAVY Index-1.21

Hydrophobic Moment 0.36

Boman Index0.05

Instability Index16.14

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 443.95

LogP -2.53

H-bond Donors 16.0

H-bond Acceptors 15.0

Rotatable Bonds 30.0

Heavy Atoms 78.0

Ring Count 5.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280193 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/