Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2316H3651N619O653S9

DescriptionStandard

        ANPGFVVRITQSGLDYAHQQGIAILEKELAQLTLPDISGDFRVMRVGKVHYELSRLRLRSFHLPYSRISPVPNVGLQVSISNAFAELDGNWRVKFFFIRDRGSFDLKVENVYIKISLRLGSDTTGKPTISTSDCSTRISKVRVLFSGKFAWLYNLFHSAVESRFRKILESKVCDTVAESVHNELQTYIRTLPVTARIDAMAGIDYSLVAPPTATAQSLDADLKGEFYSLAHRSTVPFSPLPLSFPSDHDRMVYFGASSYFFNTAGFAYHTAGALVFEITDAVIPKDVDFHLNTSVFSAFVPQLEEMYPNMPMKLRLSTLTAPFLNIGPEGISLKPVVDVQAYAILPSSSLAPLFVLSLVRNVSAVIDVRSGHIVGKLDVGRIKLSLKDSAVGTFPVRTLQSIMNILSSSILLPRLNARLDEGFPLPLPDRIRLSNTLVRFHQVSEGEHLALGHPATPKPL
    

Molecular Weight50903.10 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)6.95

Net Charge (pH 7.4) 5.99

Charge Density (pH 7.0) 0.0151

GRAVY Index0.10

Hydrophobic Moment 0.69

Boman Index0.10

Instability Index39.14

Aliphatic Index 101.91

Aromaticity 0.0935

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125847 VERIFIED: NO

Provenance & Taxonomy

OrganismSmithornis capensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria