Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC778H1230N222O234S

DescriptionStandard

        MAKFEVTPQRKAFLDAIAVGEGTDNGRQQTKNHGYDVIVGGSLFSDYSKHPGRLVKLPKLGINSTAAGRYQVLKKYAEHYIDQLNLPDFSPASQDQIALQQISERKALADIDAGRIREAVAKVNNIWASLPGSKYGQRTETIDDFLKYFRAAGGKVAGE
    

Molecular Weight17469.50 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)3.78

Net Charge (pH 7.4) 3.36

Charge Density (pH 7.0) 0.0238

GRAVY Index-0.49

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index24.88

Aliphatic Index 81.70

Aromaticity 0.0881

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 15930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7411.47

LogP -77.31

H-bond Donors 254.0

H-bond Acceptors 242.0

Rotatable Bonds 589.0

Heavy Atoms 1235.0

Ring Count 24.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0144743 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterobacteria phage IME_EC2 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic

RECORD: Rec_0413635 VERIFIED: NO