Peptide Database

Peptide NameDefensin-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC452H720N126O140S8

DescriptionStandard

        MKVLVFLAAIFLVAIQAQADPLPARTEEALDQEQFGAEDQDVPVDFAGEESSALRAAGLRSTLTCYCRSRGCSLFERLSGTCKIDNRMYYLCCR
    

Molecular Weight10415.83 Da

Isoelectric Point (pI)4.82

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.86

Charge Density (pH 7.0) -0.0376

GRAVY Index0.02

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index49.27

Aliphatic Index 86.28

Aromaticity 0.0851

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4296.92

LogP -43.59

H-bond Donors 156.0

H-bond Acceptors 145.0

Rotatable Bonds 345.0

Heavy Atoms 726.0

Ring Count 11.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426850 VERIFIED: NO

Provenance & Taxonomy

OrganismTupaia chinensis [Animal]

FamilyDefensin

Tax ID246437

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal