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MYP_091230
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Basic Information
AMP72 (De novo synthesis)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C80H150N24O19S2
Standard
Sequence
KGCALVKVRGLTLKVCK
Physicochemical Analysis
1816.33 Da
10.07
4.74
4.50
0.2786
0.54
0.39
0.00
-17.25
125.88
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
715.13
-5.44
28.0
26.0
65.0
125.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0114606 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
WI-38 (fibroblast) cells
Cytotoxicity
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0141519 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HUVEC (endothelial) cells at a peptide concentration of 100 μg/ml
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0142120 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
sheep red blood cells
500
Hemolysis
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0166715 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus agalactiae
55 μM
MBC
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
RECORD: Rec_0183508 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
PMID23893489 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23893489/
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