Peptide Database

Peptide NameSyn-safencin-40

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC138H237N43O31

DescriptionStandard

        AGKEKIRKKWKNEIKKKGRKAVIAW
    

Molecular Weight2994.63 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)8.79

Net Charge (pH 7.4) 8.59

Charge Density (pH 7.0) 0.3517

GRAVY Index-1.36

Hydrophobic Moment 0.65

Boman Index-0.45

Instability Index3.72

Aliphatic Index 70.40

Aromaticity 0.0800

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1268.97

LogP -8.11

H-bond Donors 46.0

H-bond Acceptors 40.0

Rotatable Bonds 112.0

Heavy Atoms 212.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033146 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50

RECORD: Rec_0212067 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity2.12 μM

MethodIC50