Peptide Database

Peptide NameDefensin-B1 (DefB1) (OaDefB1)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC316H523N93O88S11

DescriptionStandard

        MNAHVLLLCTILFLLVHTPPVLGGMKEKCVTMGGYCRKQCRVQDALSGYCRNENPCCVRRVLMEDG
    

Molecular Weight7385.82 Da

Isoelectric Point (pI)8.56

Net Charge (pH 7.0)2.61

Net Charge (pH 7.4) 2.18

Charge Density (pH 7.0) 0.0396

GRAVY Index0.17

Hydrophobic Moment 0.60

Boman Index0.04

Instability Index35.95

Aliphatic Index 92.88

Aromaticity 0.0455

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2896.70

LogP -26.56

H-bond Donors 107.0

H-bond Acceptors 104.0

Rotatable Bonds 245.0

Heavy Atoms 508.0

Ring Count 8.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281035 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic