Peptide Database

Peptide NameHNH endonuclease:S-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length656 amino acids

Chemical FormulaC3119H4955N923O969S6

DescriptionStandard

        MADEQEKHIYVKYWPIPDLGSADRAAAEAAANKASGGGNSGWSIGIGGGGGGPSTTGLGPGRGRRRGITNKQLRRLLRQQEAEAHALAQRQAAEHAAHLARLEAEAHARAMAEAAERERVEAQVRAQAEKDQAHRQALETLTASYPSLQSGLAQNYLLASASLPNDLQKEIASGHDLNADPPRDEQTLELILQKKTRVNYLLAIKQPLLDERRAQALSLTGQELDHATQKDHLNYLVYYSQGDPPRVQQAHEAWIQALSQTYEAKLLAESVTLLNEQSAALSMRHAELSLANKPASQDARQAAGIDKLWSVIAPASTTTAATGIRTVATNIAKDQLIRIATRTLGSNLVTLLAMYPQPLGDAELPPAVIATPLSQLNLPPHIDLHYLASVKGTLDVPHRLTSDEAGTSGAARWVATDGVEVGSKVRVRTFTYNAQNNSYEFIRDGESTPALLWTPIARPADSSTSSPAGPPALPVDPGNVVTPFVPELESYPAIDRDDPDDYILISPIDSGLPNSYLLFKDPRSIPGVASGYGEAVNGVWLGDKTRAEGASIPAHIADQLRGRRFGNFDSLRKATWIAVANDPELVKQFTQHNLEIMRDGGAPYPRLVDQAGGRTKFEIHHKKHIANGGAVYDIDNLVIMTPRQHIDHHRSHENDL
    

Molecular Weight71079.70 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-9.39

Net Charge (pH 7.4) -10.92

Charge Density (pH 7.0) -0.0143

GRAVY Index-0.44

Hydrophobic Moment 0.84

Boman Index-0.03

Instability Index43.00

Aliphatic Index 86.88

Aromaticity 0.0534

Extinction Coeff. Reduced 72310.00

Extinction Coeff. Oxidized 72310.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312267 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas syringae pv. aceris [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

MethodQualitative functional evidence