Peptide Database

Peptide NameTityustoxin TsTX-Ka

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC168H281N49O46S7

DescriptionStandard

        VFINAKCRGSPECLPKCKEAIGKAAGKCMNGKCKCYP
    

Molecular Weight3947.78 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.67

Net Charge (pH 7.4) 5.36

Charge Density (pH 7.0) 0.1533

GRAVY Index-0.28

Hydrophobic Moment 0.52

Boman Index-0.07

Instability Index47.49

Aliphatic Index 50.27

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1529.83

LogP -16.07

H-bond Donors 57.0

H-bond Acceptors 59.0

Rotatable Bonds 133.0

Heavy Atoms 270.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210048 VERIFIED: NO

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-28; 13-33; 17-35

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0355207 VERIFIED: YES