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MYP_091175
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Basic Information
Endothelin-2
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
21 amino acids
C115H164N26O32S4
Standard
Sequence
CSCSSWLDKECVYFCHLDIIW
Physicochemical Analysis
2550.95 Da
4.54
-2.19
-2.51
-0.1043
0.50
0.30
0.25
65.32
88.10
0.1905
12490.00
12740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
924.42
-4.82
37.0
35.0
78.0
177.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027528 VERIFIED: NO
Provenance & Taxonomy
Equus caballus [Animal]
Endothelin
9796
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Myotropic Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0053211 VERIFIED: NO
Provenance & Taxonomy
Canis lupus familiaris [Animal]
Endothelin
9615
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Myotropic Receptor modulation ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0069004 VERIFIED: NO
Provenance & Taxonomy
Felis catus [Animal]
Endothelin/sarafotoxin
9685
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Vasoactive Hormone
Evidence URLhttps://www.uniprot.org/uniprotkb/EDN2_FELCA/entry
RECORD: Rec_0153477 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Endothelin
9606
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0162832 VERIFIED: NO
Provenance & Taxonomy
Felis catus [Animal]
Endothelin
9685
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
1-15; 3-11
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Myotropic Receptor modulation ACE inhibitory
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
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