Peptide Database

Peptide NameSLAY-screened peptide P240

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC93H164N32O28

DescriptionStandard

        VGTSSLNGDKVPNLPRRVIR
    

Molecular Weight2178.49 Da

Isoelectric Point (pI)11.71

Net Charge (pH 7.0)2.73

Net Charge (pH 7.4) 2.52

Charge Density (pH 7.0) 0.1367

GRAVY Index-0.47

Hydrophobic Moment 0.91

Boman Index-0.20

Instability Index38.77

Aliphatic Index 102.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 994.53

LogP -12.50

H-bond Donors 35.0

H-bond Acceptors 31.0

Rotatable Bonds 71.0

Heavy Atoms 153.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414162 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/