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MYP_091049
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Basic Information
Cathelicidin 4G, buCATHL4G
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C91H124N20O16
Standard
Sequence
AIPWSIWWHLLFKG
Physicochemical Analysis
1754.08 Da
8.80
0.88
0.64
0.0630
0.61
0.32
0.55
5.29
118.57
0.2857
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
555.13
2.54
20.0
18.0
49.0
127.0
9.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0135552 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter johnsonii NCDC 0072
25 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0169035 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCDC 0111
12.5 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0227663 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028
3 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0228263 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli MTCC-0723
50 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0231177 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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