Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC430H672N122O120S12

DescriptionStandard

        MKAFSVAVAVVVVLACMFILESTAVPFSEVRTEEVESIDSPVGEHQQPGGTSMNLPMHFRFKRQSHLSLCRWCRNCCHNKGCGFCCKF
    

Molecular Weight9855.46 Da

Isoelectric Point (pI)8.17

Net Charge (pH 7.0)1.78

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0203

GRAVY Index0.14

Hydrophobic Moment 0.65

Boman Index0.08

Instability Index80.66

Aliphatic Index 69.66

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3846.12

LogP -38.52

H-bond Donors 141.0

H-bond Acceptors 138.0

Rotatable Bonds 321.0

Heavy Atoms 684.0

Ring Count 17.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090054 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmo salar [Animal]

FamilyHepcidin

Tax ID8030

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0388659 VERIFIED: NO