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MYP_090985
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Basic Information
HCV E2 HVR1 aa 384-419
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
27 amino acids
C131H198N38O39
Standard
Sequence
DTHTTGGVAGRDTLRFTGFFSFGPKQK
Physicochemical Analysis
2929.20 Da
9.99
1.85
1.59
0.0684
-0.64
0.51
-0.06
9.87
28.89
0.1481
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1254.72
-15.78
45.0
42.0
94.0
208.0
6.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0182696 VERIFIED: YES
Provenance & Taxonomy
Hepatitis C virus [Virus]
Virus-derived peptide
3052230;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
Hepatitis C virus (Translation); Huh7
Luciferase assay
PaperAmino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. | Li D, Takyar ST, Lott WB, Gowans EJ. | J Gen Virol. 2003 | PMID:12655082 PMID12655082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12655082/
RECORD: Rec_0380643 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/