Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC614H1016N184O187S10

DescriptionStandard

        MKSLLFTLAVSVLLTQLASGGWYVRKCANRTGNCRRTCRSGEVVTVPATGMCSKAKVCCLLVSQDCRPGQPSQTHTRPVTLTIQPQRVSELPTGTADTDGRARTPVGSFVVEPETLPGSQSQVMLVFPSPGAPR
    

Molecular Weight14288.41 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.14

Charge Density (pH 7.0) 0.0562

GRAVY Index-0.11

Hydrophobic Moment 0.62

Boman Index-0.00

Instability Index49.11

Aliphatic Index 76.27

Aromaticity 0.0373

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5916.03

LogP -74.58

H-bond Donors 214.0

H-bond Acceptors 206.0

Rotatable Bonds 457.0

Heavy Atoms 995.0

Ring Count 19.0

Amide Bonds 143.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178088 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocitellus parryii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence