Peptide Database

Peptide NameNeutrophil antibiotic peptide NP-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC473H760N142O148S9

DescriptionStandard

        MAMRTLTLLVALLLLAFETRAEPFEGSAEELLDQDLLGEDDQDMSISFGGDERTALQYADVRSRVTCYCRRGGCGSRESHIGYCRYRNIIYRLCCRR
    

Molecular Weight11092.54 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-2.45

Net Charge (pH 7.4) -2.83

Charge Density (pH 7.0) -0.0252

GRAVY Index-0.27

Hydrophobic Moment 0.58

Boman Index-0.11

Instability Index59.87

Aliphatic Index 84.54

Aromaticity 0.0825

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4737.05

LogP -49.15

H-bond Donors 178.0

H-bond Acceptors 156.0

Rotatable Bonds 374.0

Heavy Atoms 772.0

Ring Count 10.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083935 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyDefensin

Tax ID10029

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal